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Pharmacology



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Pharmacology - Health - 15.07.2019
Science of microdosing psychedelics ’remains patchy and anecdotal’, says review
The practice of taking small, regular doses of psychedelic drugs to enhance mood, creativity, or productivity lacks robust scientific evidence. The process, called microdosing, has been lauded by some, with high profile proponents in Silicon Valley. But to date, scientific evidence to support or even fully explore claims of the benefits and safety, has been lacking.

Pharmacology - Health - 11.07.2019
Reducing antibiotic use
Reducing antibiotic use
A simple finger-prick blood test could help prevent unnecessary prescribing of antibiotics for people with the lung condition chronic obstructive pulmonary disease (COPD), according to a new study by researchers from Cardiff University, University of Oxford and King's College London. The team demonstrated that using a CRP finger-prick blood test resulted in 20% fewer people using antibiotics for COPD flare-ups.

Pharmacology - Health - 10.07.2019
Patients with mental health conditions denied access to ’best available’ stop smoking treatments
A new study from researchers at the universities of Bristol and Bath suggests that doctors should rethink which drugs they prescribe to help smokers with mental health conditions kick the habit. Their results highlight that the most effective drug at helping individuals to stop smoking is less likely to be prescribed to people with mental health conditions.

Pharmacology - Health - 04.07.2019
Aims to improve acne in women
A new study is looking for women with acne in Bristol to take part in a new clinical trial. Led by researchers at the Universities of Bristol and Southampton the study will investigate whether a drug called spironolactone can help improve acne in women. Spironolactone is usually given to people for high blood pressure.

Pharmacology - Life Sciences - 03.07.2019
Blood pressure drug linked with increased risk of bowel condition | Imperial News | Imperial College London
Blood pressure drug linked with increased risk of bowel condition | Imperial News | Imperial College London
A type of blood pressure lowering medication, called a calcium-channel blocker, may be linked with increased risk of bowel condition diverticulosis. This condition causes small bulges or pouches to appear in the lining of the intestine. Particularly affecting the elderly (as many as 65 per cent of over 85s may be affected), diverticulosis can in some cases can lead to a medical emergency if the pouches become infected or burst.

Health - Pharmacology - 03.07.2019
Smartphone network helps uncover hundreds of anti-cancer molecules in our food
Smartphone network helps uncover hundreds of anti-cancer molecules in our food
A crowdsourcing project which uses thousands of idling smartphones has helped to uncover anti-cancer properties of everyday foods and medicines. The project, led by researchers at Imperial College London, uses artificial intelligence to crunch huge volumes of data on a ‘cloud computing' network of smartphones while they charge overnight.

Health - Pharmacology - 01.07.2019
Heart attack patients with diabetes may benefit from cholesterol-lowering drug
Injections of a cholesterol-cutting drug could reduce the risk of heart attack or stroke in patients with diabetes who have had a recent heart attack. Regular injections of a cholesterol-cutting drug could reduce the risk of heart attack or stroke in patients with diabetes and who have had a recent heart attack.

Health - Pharmacology - 10.06.2019
Improving breast cancer treatment
Millions of patients with incurable breast cancer could benefit from Welsh-led research which shows it is possible to control the cancer for twice as long by combing an investigational therapy with standard treatment. Oestrogen receptive positive breast cancer can be treated by drugs, such as fulvestrant, that interfere with the action of oestrogen.

Health - Pharmacology - 30.05.2019
'switch' that helps breast cancer spread around the body
’switch’ that helps breast cancer spread around the body
Researchers have unveiled clues into how breast cancer cells spread around the body. The early-stage research, led by scientists from Imperial College London and The Institute of Cancer Research , London, identified a genetic ‘switch' in breast cancer cells that boosts the production of a type of internal scaffolding.

Health - Pharmacology - 23.05.2019
Trial of potential new treatment for type 1 diabetes
Researchers at Cardiff and Swansea Universities are running a new trial to investigate whether a medicine currently used for the skin condition psoriasis could also be used to help people with type 1 diabetes produce some of their own insulin. Over 300,000 people in the UK have Type 1 diabetes and the drug used to treat them - insulin - has not changed in 98 years.

Pharmacology - Life Sciences - 20.05.2019
New method simplifies the search for protein receptor complexes, speeding drug development
For a drug to intervene in cells or entire organs that are not behaving normally, it must first bind to specific protein receptors in the cell membranes. Receptors can change their molecular structure in a multitude of ways during binding - and only the right structure will “unlock” the drug's therapeutic effect.

Pharmacology - Health - 14.05.2019
Decoy antibiotics could get around bacteria's defences
Decoy antibiotics could get around bacteria’s defences
Imperial medical students have helped to devise a new type of 'decoy' drug to tackle infections that are resistant to antibiotics. In tests with cell cultures, the new drug successfully killed a strain of drug-resistant bacteria. It works by delivering two antibiotics, one of which is effectively hidden.

Health - Pharmacology - 09.05.2019
Smart design could prevent drug resistance in new malaria treatments
Smart design could prevent drug resistance in new malaria treatments
Researchers have overcome malaria parasites' resistance to potential new drugs by studying how it evolves. In a paper published today in Cell Chemical Biology , scientists from the Francis Crick Institute and Imperial College London studied malaria parasites resistant to a promising new class of candidate antimalarial drugs.

Life Sciences - Pharmacology - 30.04.2019
Offers insight into the proteins in the brain that detect cannabis
Offers insight into the proteins in the brain that detect cannabis
Researchers at the University of Bristol have made new progress in understanding how cannabinoid receptors (CB1Rs), the proteins that detect the active components of marijuana, are controlled in the brain. The brain contains about 100 billion nerve cells that are constantly communicating with one another at specialised junctions called synapses.

Health - Pharmacology - 26.04.2019
Imperial launches world's first Centre for Psychedelics Research
Imperial launches world’s first Centre for Psychedelics Research
The first formal centre for psychedelic research in the world will launch at Imperial College London today. Funded by more than 3 million from five founding donors, the new Imperial Centre for Psychedelic Research will build on over a decade of pioneering work in this area carried out at Imperial, including a clinical trial that has kick-started global efforts to develop psilocybin therapy into a licensed treatment for depression.

Pharmacology - Health - 25.04.2019
Researchers in international drive to develop safer drugs
Medical researchers at the University of Nottingham and NIHR Nottingham Biomedical Research Centre are part of a major new international research project to improve the safety and regulation in the development of drugs. The team of experts in drug-induced liver injury will be members of the Translational Safety Biomarker Pipeline (TransBioLine) - a pioneering project which will generate data to support the development of novel safety biomarkers for five target organ systems (kidney, liver, pancreas, vascular and central nervous system) for use in drug development.

Pharmacology - Health - 15.04.2019
Statins fail to lower cholesterol in over half of all patients
Experts have warned a more tailored approach is needed to the prescribing of statins, following a new study suggesting they are ineffective at lowering cholesterol to target levels in more than half of patients. The research by primary care experts at The University of Nottingham, which is published in Heart , found that 51.2 per cent of patients prescribed statins saw little benefit to their cholesterol levels within two years, leading to a significant risk of developing cardiovascular disease in the future.

Health - Pharmacology - 11.04.2019
Bristol part of 20.8M study to drive drug discovery for atopic dermatitis and psoriasis
Bristol part of 20.8M study to drive drug discovery for atopic dermatitis and psoriasis
The lives of patients affected by atopic dermatitis and psoriasis could be improved thanks to the start of an EU-funded research project BIOMAP (Biomarkers in Atopic Dermatitis and Psoriasis). The five-year project will address key unmet needs in treating these common inflammatory skin conditions by analysing data from more than 50 000 patients to improve disease understanding, patient care and future therapies.

Pharmacology - Life Sciences - 10.04.2019
Active lifestyles may help nerves to heal after spinal injuries
Active lifestyles may help nerves to heal after spinal injuries
Leading an active lifestyle may increase the likelihood of damaged nerves regenerating after a spinal cord injury. The early-stage findings , published in the journal Science Translational Medicine , come from studies in mice and rats with spinal cord injuries, in which scientists uncovered a mechanism for nerve fibres repairing after they had been damaged.

Pharmacology - Health - 05.04.2019
New target for development of drugs to fight viruses
Researchers at Cardiff University have discovered that a molecule responsible for guiding virus-killing T-cells to the site of infection is also responsible for rapidly increasing T-cell numbers to fight infection, making it an important new target for the development of more effective drugs to treat both viruses and cancers.
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