Research Assistant/Associate (Fixed Term)

Closing Date
WorkplaceCambridge, East of England, UK


Job Opportunities


Research Assistant/Associate (Fixed Term)

We wish to recruit a highly driven, enthusiastic postdoctoral research scientist to join the Edgar lab to investigate the role exosomes play in MHC-II presentation. The project will combine functional immunological assays, biochemistry and molecular biology to determine what role exosomes play in MHC-II presentation, and define which molecules are found on exosomes from antigen presenting cells. The labs focuses on the physiological and pathological roles of surface-tethered exosomes, following our recent findings that exosomes may be proteinaceously tethered to the cell surface in addition to being released into the extracellular milieu.

Further reading; Tetherin is an exosomal tether. Edgar JR, Manna PT, Nishimura S, Banting G, Robinson MS. Elife. 2016 Sep 22;5. pii: e17180. doi: 10.7554/eLife.17180.

The position is funded by the Isaac Newton Trust / Wellcome Trust ISSF / University of Cambridge Joint Research Grants Scheme. This post is for 18 months, starting from 1st May 2019 in the first instance. The position will be held at a newly refurbished laboratory on Tennis Court Road at the Department of Pathology in the centre of Cambridge. The Department is well-resourced and full access to flow cytometry, imaging (fluorescence and electron microscopy) and biological services facilities are available. ?" target="_blank" rel="nofollow"> y/james-edgar

The applicant should have a PhD or equivalent in a relevant biological science.

The applicant should have the following skills:

Essential Proven track record in immunology and/or cell biology. Proven ability to deliver research at an internationally competitive level.

Desirable Candidates would have experience working with mouse models of antigen presentation, flow cytometry and biochemistry.

Key responsibilities Plan and execute experiments according to the aims of the project. Will include; record and analyse data, maintain accurate electronic records or research data, present data at lab meetings, organise the purchase, storage and record of reagents needed for the research. The successful candidate will also be expected to help supervise PhD and rotation students.

Start date: 1st May 2019

Fixed-term: The funds for this post are available for 18 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the ’Apply’ button below. This will route you to the University’s Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Any enquiries relating to the application process please contact Jodi Smith - hr [at] path[.]cam[.]

Please quote reference PK18229 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information


Department of Pathology








22 February 2019

Closing date

25 March 2019
In your application, please refer to
and reference  JobID 160568.